It was shown that after 30 seconds of in vitro direct exposure to ozone, 99 percent of the viruses are inactivated . Although this evidence is of considerable importance, outside of the laboratory models, there are various parameters that influence the time required to obtain the same result. First of all, it was seen that the inactivation of 99% of viruses by ozonation requires its spread at concentrations higher than those necessary for the bacteria . A longer exposure time, about 30 minutes, is necessary for the treatment of the surfaces of the environment (surface viruses), while for any viral particles suspended in the air (airborne viruses) 8-10 minutes are enough to remove 99.9% of them . Viruses in water are more susceptible to ozone inactivation and short contact time, about 1 min or little more, are sufficient to inactivate 99% of them